Is 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate? Is 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate safe for nursing mother and child? Does 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate extracts into breast milk? Does 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate has any long term or short term side effects on infants? Can 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate influence milk supply or can 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate decrease milk supply in lactating mothers?
4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate lactation summary
- DrLact safety Score for 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate usage in lactation
Advice to take a minimal dose for a short time since anti-cholinergic drugs may decrease breast milk production. Check-up for anti-cholinergic symptoms (mouth dryness, constipation...)
Answer by DrLact: About 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate usage in lactation
No information is available on the use of oxybutynin during breastfeeding. Long-term use of oxybutynin might reduce milk production or milk letdown, but a single dose is not likely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).
4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate Possible Effects in Breastfeeding
Anticholinergics can inhibit lactation in animals apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed. The manufacturer reports that cases of lactation suppression have been reported with some oxybutynin (immediate-release) formulations in postmarketing surveillance.[7]
Alternate Drugs
Solifenacin(Unsafe)
Flavoxate(Low Risk)
Scopolamine(Low Risk)
Fesoterodine(Low Risk)
Ipratropium(Safe)
Oxybutinyn(Low Risk)
Glycopyrrolate(Unsafe)
Atropine(Safe)
Tropicamide(Low Risk)
Dicyclomine(Unsafe)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Flavoxate(Low Risk)
Scopolamine(Low Risk)
Fesoterodine(Low Risk)
Ipratropium(Safe)
Oxybutinyn(Low Risk)
Glycopyrrolate(Unsafe)
Atropine(Safe)
Tropicamide(Low Risk)
Dicyclomine(Unsafe)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Solifenacin(Unsafe)