Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-8L5014XET7? Is UNII-8L5014XET7 safe for nursing mother and child? Does UNII-8L5014XET7 extracts into breast milk? Does UNII-8L5014XET7 has any long term or short term side effects on infants? Can UNII-8L5014XET7 influence milk supply or can UNII-8L5014XET7 decrease milk supply in lactating mothers?

UNII-8L5014XET7 lactation summary

UNII-8L5014XET7 is unsafe in breastfeeding
  • DrLact safety Score for UNII-8L5014XET7 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of UNII-8L5014XET7 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-8L5014XET7 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using UNII-8L5014XET7 .
  • It is recommended to evaluate the advantage of not breastfeeding while using UNII-8L5014XET7 Vs not using UNII-8L5014XET7 And continue breastfeeding.
  • While using UNII-8L5014XET7 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-8L5014XET7 usage in lactation

It is an alpha-1-adrenergic blocking agent that is used for treatment of arterial hypertension. Also, used in men for treatment of benign prostate hypertrophy. At latest update, relevant published data on excretion into breast milk were not found. Because of its pharmacokinetics (moderately high molecular weight and high protein-binding capacity) excretion into breast milk in significant amount is unlikely. Since it may be cause of arterial hypotension in the infant, safer options are preferred especially during the neonatal period and in case of prematurity.

Answer by DrLact: About UNII-8L5014XET7 usage in lactation

Because no information is available on the use of UNII-8L5014XET7 during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

UNII-8L5014XET7 Possible Effects in Breastfeeding

Relevant published information in nursing mothers was not found as of the revision date. However, the pharmacologically similar drug prazosin does not affect serum prolactin concentration in patients with hypertension.[1][2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.