Is AL-6221 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use AL-6221? Is AL-6221 safe for nursing mother and child? Does AL-6221 extracts into breast milk? Does AL-6221 has any long term or short term side effects on infants? Can AL-6221 influence milk supply or can AL-6221 decrease milk supply in lactating mothers?

AL-6221 lactation summary

DrLact safety Score for AL-6221 is 1 out of 8 which is considered Safe as per our analyses.
A safety Score of 1 indicates that usage of AL-6221 is mostly safe during lactation for breastfed baby.
Our study of different scientific research also indicates that AL-6221 does not cause any serious side effects in breastfeeding mothers.
Most of scientific studies and research papers declaring usage of AL-6221 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About AL-6221 usage in lactation

It does occurr a minimal absorption into systemic circulation. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding.

Answer by DrLact: About AL-6221 usage in lactation

No information is available on the use of AL-6221 during breastfeeding. Because of its short half-life it is not likely to reach the bloodstream of the infant or cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Alternate Drugs

Unoprostone

Acetazolamide(Safe)

Timolol(Safe)

Travoprost(Safe)

Metipranolol

Pilocarpine(Unsafe)

Levobunolol(Low Risk)

Methazolamide

Betaxolol

Dorzolamide

Latanoprost(Safe)

Epinephrine(Safe)

Brinzolamide(Low Risk)

Brimonidine(Safe)

Bimatoprost(Safe)

Carteolol(Unsafe)

Phenylephrine(Low Risk)

Misoprostol(Safe)

Travoprost(Safe)

Latanoprost(Safe)

Dinoprostone(Low Risk)

Bimatoprost(Safe)

Synonyms of AL-6221

Travatan

5-Heptenoic acid, 7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl ester, (1R-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-

(((1R)-(1alpha(Z),2beta(1E,3R*),3alpha,5alpha))-7-(3,5-dihydroxy-2-(3-hydroxy-4-(3-trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-5-heptenoic acid, 1-methylethyl ester

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.