Question

I am a breastfeeding mother and i want to know if it is safe to use 5-20-02-00231 (Beilstein Handbook Reference)? Is 5-20-02-00231 (Beilstein Handbook Reference) safe for nursing mother and child? Does 5-20-02-00231 (Beilstein Handbook Reference) extracts into breast milk? Does 5-20-02-00231 (Beilstein Handbook Reference) has any long term or short term side effects on infants? Can 5-20-02-00231 (Beilstein Handbook Reference) influence milk supply or can 5-20-02-00231 (Beilstein Handbook Reference) decrease milk supply in lactating mothers?

Answer by DrLact: About 5-20-02-00231 (Beilstein Handbook Reference) usage in lactation

Limited information indicates that maternal doses of 5-20-02-00231 (Beilstein Handbook Reference) up to 4 mg daily together with haloperidol did not produce any adverse effects in breastfed infants. Long-term use of 5-20-02-00231 (Beilstein Handbook Reference) might reduce milk production or milk letdown, but a single dose is not likely to interfere with breastfeeding. During long-term use, observe for signs of decreased lactation (e.g., insatiety, poor weight gain).

5-20-02-00231 (Beilstein Handbook Reference) Side Effects in Breastfeeding

One woman with schizophrenia took 5-20-02-00231 (Beilstein Handbook Reference) and haloperidol during 3 pregnancies and postpartum. The 5-20-02-00231 (Beilstein Handbook Reference) dose was 4 mg daily in all 3 pregnancies. She breastfed (extent not stated) all 3 children for 6 to 8 months using the same doses. Development was age-appropriate in all children aged 16 months at 8 years of age at the time of assessment.[1]

5-20-02-00231 (Beilstein Handbook Reference) Possible Effects in Breastfeeding

Anticholinergics can inhibit lactation in animals, apparently by inhibiting growth hormone and oxytocin secretion.[2][3][4][5][6] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed. One woman with schizophrenia took 5-20-02-00231 (Beilstein Handbook Reference) and haloperidol during 3 pregnancies and postpartum. She was able to breastfeed (extent not stated) all 3 children for 6 to 8 months.[1] The prolactin elevating effect of haloperidol might have counteracted any prolactin lowering effect of 5-20-02-00231 (Beilstein Handbook Reference).
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