Is Dextro-amphetamine Sulfate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Dextro-amphetamine Sulfate? Is Dextro-amphetamine Sulfate safe for nursing mother and child? Does Dextro-amphetamine Sulfate extracts into breast milk? Does Dextro-amphetamine Sulfate has any long term or short term side effects on infants? Can Dextro-amphetamine Sulfate influence milk supply or can Dextro-amphetamine Sulfate decrease milk supply in lactating mothers?
Dextro-amphetamine Sulfate lactation summary
- DrLact safety Score for Dextro-amphetamine Sulfate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Dextro-amphetamine Sulfate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Dextro-amphetamine Sulfate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Dextro-amphetamine Sulfate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Dextro-amphetamine Sulfate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Dextro-amphetamine Sulfate usage in lactation
A sympathomimetic drug and central nervous system stimulant, it has a similar action and uses to amphetamine, its dextro isomer.It is used (GSK, 2007) in the treatment of narcolepsy (Wise, 2007) and Attention Deficit Hyperactivity Disorder (ADHD), and is also used as an illegal drug (Oei, 2012). It is excreted in breast milk, concentrating about 3 times more than in plasma. This concentration assumes a relative dose about 6% (Ilett, 2007). In infants whose mothers were taking dexamfetamine as treatment for ADHD, levels ranging from undetectable to 14% of maternal plasma levels have been measured and no problems were observed in the clinical follow-up of these infants (Ilett, 2007). There is little information on the impact of amphetamine abuse on the development and health of infants (Oei, 2012, Wise, 2007; Moretti, 2000), but it is known that they are more exposed to social problems, domestic violence, and lower breastfeeding rates (Oei, 2010). There is controversy over the possibly mild negative effect of amphetamine on prolactin (Petraglia, 1987; DeLeo, 1983), but milk production in mothers who took it therapeutically was not affected (Öhman, 2015). During breastfeeding, the therapeutic use (narcolepsy, ADHD) of dexamphetamine can be assessed, using the lowest possible effective dose and monitoring the occurrence of irritability, insomnia, lack of appetite and weight loss. Its use as an illegal drug is totally discouraged (Oei, 2012). See below the information of these related products: