Is N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide? Is N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide safe for nursing mother and child? Does N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide extracts into breast milk? Does N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide has any long term or short term side effects on infants? Can N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide influence milk supply or can N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide decrease milk supply in lactating mothers?
N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide lactation summary
- DrLact safety Score for N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide usage in lactation
Use a minimal dose as possible. When applying, press with a finger on conjunctival sac for 2 minutes to avoid systemic absorption. (Cholinergic effects are likely)
Answer by DrLact: About N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide usage in lactation
No information is available on the use of N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide during breastfeeding. Anticholinergic drugs might interfere with breastfeeding. A single dose of ophthalmic N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide is not likely to interfere with breastfeeding; however, during long-term use, observe the infant for signs of decreased lactation (e.g., insatiety, poor weight gain). To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.
N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide Possible Effects in Breastfeeding
Relevant published information in nursing mothers was not found as of the revision date. Anticholinergics can inhibit lactation in animals apparently by inhibiting growth hormone and oxytocin secretion.[1][2][3][4][5] Anticholinergic drugs can also reduce serum prolactin in nonnursing women.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Alternate Drugs
Tropicamide(Low Risk)
Glycopyrrolate(Unsafe)
Atropine(Safe)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Dicyclomine(Unsafe)
Flavoxate(Low Risk)
Solifenacin(Unsafe)
Fesoterodine(Low Risk)
Oxybutinyn(Low Risk)
Scopolamine(Low Risk)
Ipratropium(Safe)
Tropicamide(Low Risk)
Epinephrine(Safe)
Atropine(Safe)
Cyclopentolate(Low Risk)
Scopolamine(Low Risk)
Glycopyrrolate(Unsafe)
Atropine(Safe)
Cyclopentolate(Low Risk)
Tolterodine(Low Risk)
Dicyclomine(Unsafe)
Flavoxate(Low Risk)
Solifenacin(Unsafe)
Fesoterodine(Low Risk)
Oxybutinyn(Low Risk)
Scopolamine(Low Risk)
Ipratropium(Safe)
Tropicamide(Low Risk)