Question

I am a breastfeeding mother and i want to know if it is safe to use 4-Guanidino-Neu5Ac2en? Is 4-Guanidino-Neu5Ac2en safe for nursing mother and child? Does 4-Guanidino-Neu5Ac2en extracts into breast milk? Does 4-Guanidino-Neu5Ac2en has any long term or short term side effects on infants? Can 4-Guanidino-Neu5Ac2en influence milk supply or can 4-Guanidino-Neu5Ac2en decrease milk supply in lactating mothers?

4-Guanidino-Neu5Ac2en lactation summary

4-Guanidino-Neu5Ac2en is safe in breastfeeding
  • DrLact safety Score for 4-Guanidino-Neu5Ac2en is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of 4-Guanidino-Neu5Ac2en is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that 4-Guanidino-Neu5Ac2en does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of 4-Guanidino-Neu5Ac2en safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 4-Guanidino-Neu5Ac2en usage in lactation

Prophylaxis and treament of Influenza virus disease. A low excrection into breast milk and low oral biodisponibility, both characteristics make it even safer while breastfeeding. No adverse effects have been shown in breastfed infants.

Answer by DrLact: About 4-Guanidino-Neu5Ac2en usage in lactation

No information is available on the use of 4-Guanidino-Neu5Ac2en during breastfeeding. One group of authors estimated that an exclusively breastfed 5 kg infant would receive about 0.075 mg daily in breastmilk after an inhaled maternal dose of 10 mg, which is less than 1% of the dose in older children. In addition, because 4-Guanidino-Neu5Ac2en is poorly absorbed orally, it is not likely to reach the bloodstream of the infant in clinically important amounts.[1]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.