Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7478? Is HSDB 7478 safe for nursing mother and child? Does HSDB 7478 extracts into breast milk? Does HSDB 7478 has any long term or short term side effects on infants? Can HSDB 7478 influence milk supply or can HSDB 7478 decrease milk supply in lactating mothers?

HSDB 7478 lactation summary

HSDB 7478 usage has low risk in breastfeeding
  • DrLact safety Score for HSDB 7478 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of HSDB 7478 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that HSDB 7478 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of HSDB 7478 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using HSDB 7478 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7478 usage in lactation

Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics.

Answer by DrLact: About HSDB 7478 usage in lactation

HSDB 7478 is excreted into breastmilk in concentration likely to be effective against staphylococcal strains found in mastitis.[1][2][3] Limited data indicate that the maximum dose an infant would receive through breastmilk would be much less than the standard infant dose and that resulting infant serum levels are trivial. If HSDB 7478 is required by the mother, it is not a reason to discontinue breastfeeding. Monitor the infant for possible effects on the gastrointestinal tract, such as diarrhea, vomiting, and candidiasis (e.g., thrush, diaper rash). However, because there is no published experience with HSDB 7478 during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Alternate Drugs

Linezolid(Low Risk)
Amantadine(Low Risk)
Tenofovir(Safe)
Cefoxitin(Safe)
Gatifloxacin(Low Risk)
Ofloxacin(Safe)
Cefotetan(Safe)
Efavirenz(Unsafe)
Enoxacin(Low Risk)
Didanosine(Unsafe)
Doxycycline(Low Risk)
Amikacin(Safe)
Saquinavir(Unsafe)
Neomycin(Safe)
Valganciclovir(Low Risk)
Naftifine(Safe)
Nafcillin(Safe)
Ganciclovir(Low Risk)
Cefixime(Safe)
Demeclocycline(Low Risk)
Ritonavir(Unsafe)
Moxifloxacin(Low Risk)
Cefepime(Safe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Abacavir(Safe)
Malathion(Low Risk)
Famciclovir(Low Risk)
Nevirapine(Low Risk)
Methicillin(Low Risk)
Cefdinir(Safe)
Erythromycin(Low Risk)
Nelfinavir(Unsafe)
Meropenem(Safe)
Lindane(Unsafe)
Cefazolin(Safe)
Linezolid(Low Risk)
Clindamycin(Low Risk)
Lomefloxacin(Low Risk)
Cefaclor(Safe)
Levofloxacin(Low Risk)
Dapsone(Low Risk)
Econazole(Safe)
Kanamycin(Safe)
Capreomycin(Low Risk)
Rifaximin(Safe)
Indinavir(Unsafe)
Ertapenem(Safe)
Acyclovir(Safe)
Aztreonam(Safe)
Zidovudine(Low Risk)
Cefprozil(Safe)
Quinine(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.