Is DRG-0084 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use DRG-0084? Is DRG-0084 safe for nursing mother and child? Does DRG-0084 extracts into breast milk? Does DRG-0084 has any long term or short term side effects on infants? Can DRG-0084 influence milk supply or can DRG-0084 decrease milk supply in lactating mothers?
DRG-0084 lactation summary
- DrLact safety Score for DRG-0084 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of DRG-0084 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that DRG-0084 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of DRG-0084 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using DRG-0084 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About DRG-0084 usage in lactation
Drug used for treatment and prophylaxis of Pneumoystis pneumonia. Also used in combination with Proguanil for treatment of malaria. On latest update relevant data on breastfeeding was not found. Pharmacokinetic data indicates that drug excretion into breast milk would not be significant. It has been approved to treat infants over 5 kg of body weight. May be used in nursing mothers of newborn and babies under 5 kg of body weight since benefit is greater than risk.
Answer by DrLact: About DRG-0084 usage in lactation
No information is available on the use of DRG-0084 during breastfeeding. However, the quantity of drug in breast milk is assumed too low to provide adequate protection against malaria for the breastfed infant.[1] A dosage has been established for infants weighing as little as 5 kg, so it is unlikely to adversely affect breastfed infants weighing 5 kg or more.
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