Is Tolbutamide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Tolbutamide? Is Tolbutamide safe for nursing mother and child? Does Tolbutamide extracts into breast milk? Does Tolbutamide has any long term or short term side effects on infants? Can Tolbutamide influence milk supply or can Tolbutamide decrease milk supply in lactating mothers?
Tolbutamide lactation summary
- DrLact safety Score for Tolbutamide is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Tolbutamide is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Tolbutamide does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Tolbutamide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Tolbutamide usage in lactation
Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About Tolbutamide usage in lactation
Tolbutamide is excreted into breastmilk in small amounts that should cause no harm to the breastfed infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]
Alternate Drugs
Glimepiride(Unsafe)
Miglitol(Safe)
Dulaglutide(Low Risk)
Chlorpropamide(Low Risk)
Tolbutamide(Safe)
Liraglutide(Low Risk)
Acetohexamide(Low Risk)
Acarbose(Safe)
Rosiglitazone(Low Risk)
Repaglinide(Unsafe)
Pioglitazone(Low Risk)
Empagliflozin(Unsafe)
Nateglinide(Unsafe)
Dapagliflozin(Unsafe)
Metformin(Safe)
Alogliptin(Low Risk)
Insulin(Safe)
Linagliptin(Low Risk)
Glyburide(Safe)
Sitagliptin(Low Risk)
Saxagliptin(Low Risk)
Glipizide(Safe)
Colesevelam(Safe)
Chlorpropamide(Low Risk)
Tolbutamide(Safe)
Acetohexamide(Low Risk)
Glyburide(Safe)
Glipizide(Safe)
Glimepiride(Unsafe)