Question

I am a breastfeeding mother and i want to know if it is safe to use Primotest? Is Primotest safe for nursing mother and child? Does Primotest extracts into breast milk? Does Primotest has any long term or short term side effects on infants? Can Primotest influence milk supply or can Primotest decrease milk supply in lactating mothers?

Primotest lactation summary

Primotest usage has low risk in breastfeeding
  • DrLact safety Score for Primotest is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Primotest may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Primotest may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Primotest low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Primotest We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Primotest usage in lactation

Primotest hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of Primotest serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.

Answer by DrLact: About Primotest usage in lactation

Limited data indicate that a low-dose (100 mg) subcutaneous Primotest pellet given to a nursing mother appears not to increase milk Primotest levels markedly. Primotest has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal Primotest therapy.

Primotest Side Effects in Breastfeeding

An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of Primotest subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]

Primotest Possible Effects in Breastfeeding

Supraphysiologic serum levels of Primotest, either from a tumor[2][3] or from exogenously administered Primotest,[4] reduces milk production in postpartum women. Primotest alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] Primotest was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.