Question

I am a breastfeeding mother and i want to know if it is safe to use Synandrol F? Is Synandrol F safe for nursing mother and child? Does Synandrol F extracts into breast milk? Does Synandrol F has any long term or short term side effects on infants? Can Synandrol F influence milk supply or can Synandrol F decrease milk supply in lactating mothers?

Synandrol F lactation summary

Synandrol F usage has low risk in breastfeeding
  • DrLact safety Score for Synandrol F is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Synandrol F may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Synandrol F may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Synandrol F low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Synandrol F We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Synandrol F usage in lactation

Synandrol F hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of Synandrol F serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.

Answer by DrLact: About Synandrol F usage in lactation

Limited data indicate that a low-dose (100 mg) subcutaneous Synandrol F pellet given to a nursing mother appears not to increase milk Synandrol F levels markedly. Synandrol F has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal Synandrol F therapy.

Synandrol F Side Effects in Breastfeeding

An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of Synandrol F subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]

Synandrol F Possible Effects in Breastfeeding

Supraphysiologic serum levels of Synandrol F, either from a tumor[2][3] or from exogenously administered Synandrol F,[4] reduces milk production in postpartum women. Synandrol F alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] Synandrol F was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
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