Is COL 1621 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use COL 1621? Is COL 1621 safe for nursing mother and child? Does COL 1621 extracts into breast milk? Does COL 1621 has any long term or short term side effects on infants? Can COL 1621 influence milk supply or can COL 1621 decrease milk supply in lactating mothers?
COL 1621 lactation summary
- DrLact safety Score for COL 1621 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of COL 1621 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that COL 1621 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of COL 1621 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using COL 1621 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About COL 1621 usage in lactation
COL 1621 hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of COL 1621 serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.
Answer by DrLact: About COL 1621 usage in lactation
Limited data indicate that a low-dose (100 mg) subcutaneous COL 1621 pellet given to a nursing mother appears not to increase milk COL 1621 levels markedly. COL 1621 has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal COL 1621 therapy.
COL 1621 Side Effects in Breastfeeding
An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of COL 1621 subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]
COL 1621 Possible Effects in Breastfeeding
Supraphysiologic serum levels of COL 1621, either from a tumor[2][3] or from exogenously administered COL 1621,[4] reduces milk production in postpartum women. COL 1621 alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] COL 1621 was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
Alternate Drugs
Testosterone(Low Risk)
Estradiol Valerate(Low Risk)
Testosterone(Low Risk)
Progesterone(Safe)
Estradiol(Low Risk)