Question

I am a breastfeeding mother and i want to know if it is safe to use AA 2500? Is AA 2500 safe for nursing mother and child? Does AA 2500 extracts into breast milk? Does AA 2500 has any long term or short term side effects on infants? Can AA 2500 influence milk supply or can AA 2500 decrease milk supply in lactating mothers?

AA 2500 lactation summary

AA 2500 usage has low risk in breastfeeding
  • DrLact safety Score for AA 2500 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of AA 2500 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that AA 2500 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of AA 2500 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using AA 2500 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About AA 2500 usage in lactation

AA 2500 hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of AA 2500 serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.

Answer by DrLact: About AA 2500 usage in lactation

Limited data indicate that a low-dose (100 mg) subcutaneous AA 2500 pellet given to a nursing mother appears not to increase milk AA 2500 levels markedly. AA 2500 has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal AA 2500 therapy.

AA 2500 Side Effects in Breastfeeding

An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of AA 2500 subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]

AA 2500 Possible Effects in Breastfeeding

Supraphysiologic serum levels of AA 2500, either from a tumor[2][3] or from exogenously administered AA 2500,[4] reduces milk production in postpartum women. AA 2500 alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] AA 2500 was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.