Is CP 601B Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use CP 601B? Is CP 601B safe for nursing mother and child? Does CP 601B extracts into breast milk? Does CP 601B has any long term or short term side effects on infants? Can CP 601B influence milk supply or can CP 601B decrease milk supply in lactating mothers?
CP 601B lactation summary
- DrLact safety Score for CP 601B is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of CP 601B may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that CP 601B may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of CP 601B low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using CP 601B We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About CP 601B usage in lactation
CP 601B hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of CP 601B serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.
Answer by DrLact: About CP 601B usage in lactation
Limited data indicate that a low-dose (100 mg) subcutaneous CP 601B pellet given to a nursing mother appears not to increase milk CP 601B levels markedly. CP 601B has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal CP 601B therapy.
CP 601B Side Effects in Breastfeeding
An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of CP 601B subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]
CP 601B Possible Effects in Breastfeeding
Supraphysiologic serum levels of CP 601B, either from a tumor[2][3] or from exogenously administered CP 601B,[4] reduces milk production in postpartum women. CP 601B alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] CP 601B was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
Alternate Drugs
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