Question

I am a breastfeeding mother and i want to know if it is safe to use Striant? Is Striant safe for nursing mother and child? Does Striant extracts into breast milk? Does Striant has any long term or short term side effects on infants? Can Striant influence milk supply or can Striant decrease milk supply in lactating mothers?

Striant lactation summary

Striant usage has low risk in breastfeeding
  • DrLact safety Score for Striant is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Striant may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Striant may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Striant low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Striant We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Striant usage in lactation

Striant hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of Striant serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.

Answer by DrLact: About Striant usage in lactation

Limited data indicate that a low-dose (100 mg) subcutaneous Striant pellet given to a nursing mother appears not to increase milk Striant levels markedly. Striant has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal Striant therapy.

Striant Side Effects in Breastfeeding

An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of Striant subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]

Striant Possible Effects in Breastfeeding

Supraphysiologic serum levels of Striant, either from a tumor[2][3] or from exogenously administered Striant,[4] reduces milk production in postpartum women. Striant alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] Striant was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.