Is UNII-3XMK78S47O Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-3XMK78S47O? Is UNII-3XMK78S47O safe for nursing mother and child? Does UNII-3XMK78S47O extracts into breast milk? Does UNII-3XMK78S47O has any long term or short term side effects on infants? Can UNII-3XMK78S47O influence milk supply or can UNII-3XMK78S47O decrease milk supply in lactating mothers?
UNII-3XMK78S47O lactation summary
- DrLact safety Score for UNII-3XMK78S47O is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-3XMK78S47O may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-3XMK78S47O may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-3XMK78S47O low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-3XMK78S47O We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-3XMK78S47O usage in lactation
UNII-3XMK78S47O hormone reduces Prolactin serum levels and may likely inhibit milk production mainly soon after delivery. No significant increase of UNII-3XMK78S47O serum levels neither in the mother´s milk nor in the infant’s serum have been found after administration to the mother. No adverse side effects have been noticed in the infant.
Answer by DrLact: About UNII-3XMK78S47O usage in lactation
Limited data indicate that a low-dose (100 mg) subcutaneous UNII-3XMK78S47O pellet given to a nursing mother appears not to increase milk UNII-3XMK78S47O levels markedly. UNII-3XMK78S47O has low oral bioavailability because of extensive first-pass metabolism, so it is unlikely to affect the breastfed infant. One breastfed infant seemed not to be adversely affected by low-dose maternal UNII-3XMK78S47O therapy.
UNII-3XMK78S47O Side Effects in Breastfeeding
An infant (age not stated) was breastfed (extent not stated) after implantation of 100 mg of UNII-3XMK78S47O subcutaneously. No adverse effects were noted in the infant over a 5-month period.[1]
UNII-3XMK78S47O Possible Effects in Breastfeeding
Supraphysiologic serum levels of UNII-3XMK78S47O, either from a tumor[2][3] or from exogenously administered UNII-3XMK78S47O,[4] reduces milk production in postpartum women. UNII-3XMK78S47O alone reduces serum prolactin;[4] however, when given in combination with estrogen and progestin, serum prolactin levels are not markedly reduced.[5] UNII-3XMK78S47O was previously used therapeutically to suppress lactation, usually in combination with an estrogen.[4][5][6][7][8][9][10]
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