Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3085? Is HSDB 3085 safe for nursing mother and child? Does HSDB 3085 extracts into breast milk? Does HSDB 3085 has any long term or short term side effects on infants? Can HSDB 3085 influence milk supply or can HSDB 3085 decrease milk supply in lactating mothers?

HSDB 3085 lactation summary

HSDB 3085 is unsafe in breastfeeding
  • DrLact safety Score for HSDB 3085 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of HSDB 3085 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that HSDB 3085 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using HSDB 3085 .
  • It is recommended to evaluate the advantage of not breastfeeding while using HSDB 3085 Vs not using HSDB 3085 And continue breastfeeding.
  • While using HSDB 3085 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 3085 usage in lactation

No data on breastfeeding mothers is available. Better option would be to use anxiolytic drugs known to be safer. Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About HSDB 3085 usage in lactation

No information is available on the excretion of HSDB 3085 into breastmilk. One case of infant sedation was reported in a woman taking HSDB 3085 along with other sedating drugs during breastfeeding. Because of the long duration of action of HSDB 3085, an alternate hypnotic is preferred, especially while nursing a newborn or preterm infant.

HSDB 3085 Side Effects in Breastfeeding

In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. One mother who was taking HSDB 3085 (dose unclear), clonazepam 0.25 mg twice daily, 1 mg of bupropion daily, and 0.75 mg of risperidone daily reported sedation in her breastfed infant.[1]

Alternate Drugs

Nitrazepam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Diazepam(Low Risk)
Clorazepate(Low Risk)
Clobazam(Low Risk)
Clonazepam(Low Risk)
Temazepam(Low Risk)
Estazolam(Low Risk)
Alprazolam(Low Risk)
Quazepam(Unsafe)
Flurazepam(Unsafe)
Oxazepam(Safe)
Secobarbital(Low Risk)
Nitrazepam(Low Risk)
Midazolam(Safe)
Propofol(Safe)
Lorazepam(Safe)
Eszopiclone(Low Risk)
Chloral Hydrate(Low Risk)
Diazepam(Low Risk)
Zolpidem(Safe)
Ketamine(Low Risk)
Zaleplon(Safe)
Clorazepate(Low Risk)
Triazolam(Low Risk)
Estazolam(Low Risk)
Temazepam(Low Risk)
Flurazepam(Unsafe)
Alprazolam(Low Risk)
Quazepam(Unsafe)
Meprobamate(Low Risk)
Phenobarbital(Low Risk)
Butalbital(Low Risk)
Sodium Oxybate(Low Risk)
Butabarbital(Low Risk)
Oxazepam(Safe)
Pentobarbital(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.