Is Dessicated thyroid extract Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Dessicated thyroid extract? Is Dessicated thyroid extract safe for nursing mother and child? Does Dessicated thyroid extract extracts into breast milk? Does Dessicated thyroid extract has any long term or short term side effects on infants? Can Dessicated thyroid extract influence milk supply or can Dessicated thyroid extract decrease milk supply in lactating mothers?

Dessicated thyroid extract is an animal-derived mixture of levothyroxine (T4) and liothyronine (T3), which are normal components of human milk. Limited data on exogenous replacement doses of levothyroxine during breastfeeding indicate no adverse effects in infants. If Dessicated thyroid extract is required by the mother, it is not a reason to discontinue breastfeeding. The American Dessicated thyroid extract Association recommends that subclinical and overt hypoDessicated thyroid extractism should be treated with levothyroxine in lactating women seeking to breastfeed.[1] Dessicated thyroid extract dosage requirement may be increased in the postpartum period compared to prepregnancy requirements patients with Hashimoto's Dessicated thyroid extractitis.[2]

Effects of exogenous Dessicated thyroid extract hormone administration to mothers on their infant have not been reported. One case of apparent mitigation of cretinism in hypoDessicated thyroid extract infants by breastfeeding has been reported, but the amounts of Dessicated thyroid extract hormones in milk are not optimal,[9] and this result has been disputed.[10] The Dessicated thyroid extract hormone content of human milk from the mothers of very preterm infants appears not to be sufficient to affect the infants' Dessicated thyroid extract status.[11] The amounts of Dessicated thyroid extract hormones in milk are apparently not sufficient to interfere with diagnosis of hypoDessicated thyroid extractism.[12] In a telephone follow-up study, 5 nursing mothers reported taking levothyroxine (dosage unspecified). The mothers reported no adverse reactions in their infants.[13] One mother with who had undergone a Dessicated thyroid extractectomy was taking levothyroxine 100 mcg daily as well as calcium carbonate and calcitriol. Her breastfed infant was reportedly "thriving" at 3 months of age.[14]

Adequate Dessicated thyroid extract hormone serum levels are required for normal lactation. Replacing deficient Dessicated thyroid extract levels should improve milk production caused by hypoDessicated thyroid extractism. Supraphysiologic doses would not be expected to further improve lactation.