Question

I am a breastfeeding mother and i want to know if it is safe to use Norpregneninolone? Is Norpregneninolone safe for nursing mother and child? Does Norpregneninolone extracts into breast milk? Does Norpregneninolone has any long term or short term side effects on infants? Can Norpregneninolone influence milk supply or can Norpregneninolone decrease milk supply in lactating mothers?

Norpregneninolone lactation summary

Norpregneninolone is safe in breastfeeding
  • DrLact safety Score for Norpregneninolone is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Norpregneninolone is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Norpregneninolone does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Norpregneninolone safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Norpregneninolone usage in lactation

Progestin contraceptive used as a single product or linked to ethinyl estradiol (see Etinilestradiol + Norethindrone). Norethindrone is a progestin derivative of 19-nortestosterone. It is excreted in breast milk in clinically significant amount and no problems have been observed in infants whose mothers took it. Plasma levels of these infants were undetectable or very low. Progestin is generally considered contraceptive drugs of choice during lactation since it neither alter the quantity and composition of milk nor cause side effects on both growth of infants and the duration of breastfeeding.Published study results have shown protection against breast bone mass loss with the use of progestin-only contraceptives. For the first 6 weeks postpartum, non-hormonal methods are of choise. There is a debate on the role of progestin-related drugs in decreasing milk production when used before lactation has been fully established. The American Academy of Pediatrics states that this medication is usually compatible with breastfeeding.WHO List of Essential Medicines 2002: rates it as compatible with breastfeeding after the 6th postnatal week.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.