Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3161? Is HSDB 3161 safe for nursing mother and child? Does HSDB 3161 extracts into breast milk? Does HSDB 3161 has any long term or short term side effects on infants? Can HSDB 3161 influence milk supply or can HSDB 3161 decrease milk supply in lactating mothers?

Answer by DrLact: About HSDB 3161 usage in lactation

No information is available on the use of HSDB 3161 during breastfeeding.

HSDB 3161 Possible Effects in Breastfeeding

Relevant published information in nursing mothers was not found as of the revision date. In animals, cholinergic drugs increase oxytocin release,[2] and have variable effects on serum prolactin.[3] HSDB 3161 increases serum prolactin in humans.[4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs

Pyridostigmine(Safe)
Edrophonium
Physostigmine
Echothiophate
Neostigmine
Pyridostigmine(Safe)
Edrophonium
Physostigmine
Pilocarpine(Unsafe)
Echothiophate
Carbachol(Low Risk)
Bethanechol(Unsafe)
Acetylcholine
Neostigmine

Synonyms of HSDB 3161

Antilirium
Calabarine
Carbamic acid, methyl-, ester with eseroline
CCRIS 3422
CS 58525
EINECS 200-332-8
Eserine
Eserolein, methylcarbamate (ester)
Esromiotin
Ezerin
Fysostigmin [Czech]
(3aS-cis)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo(2,3-b)indol-5-ol methylcarbamate (ester)
MCV 4484
Methyl-carbamic acid, ester with eseroline
NIH 10421
NSC 30782
Physostol
Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-, methylcarbamate (ester), (3aS-cis)-
Fysostigmin
UNII-9U1VM840SP
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