Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7583? Is HSDB 7583 safe for nursing mother and child? Does HSDB 7583 extracts into breast milk? Does HSDB 7583 has any long term or short term side effects on infants? Can HSDB 7583 influence milk supply or can HSDB 7583 decrease milk supply in lactating mothers?

Answer by DrLact: About HSDB 7583 usage in lactation

The excretion of HSDB 7583 alfa in breastmilk or its effects on breastfed infants have not been studied. However, erythropoietin is a normal component of human milk and HSDB 7583 is immunologically and biologically indistinguishable from native erythropoietin. Intravenous HSDB 7583 has been given safely to newborn infants in doses much larger than those expected to appear in breastmilk. No special precautions are required during breastfeeding.

HSDB 7583 Side Effects in Breastfeeding

Enhancement of gastrointestinal tract maturation has been proposed as a function of erythropoietin in breastmilk.[1][8]

HSDB 7583 Possible Effects in Breastfeeding

In small studies, epoetin alfa administration decreased serum prolactin in patients with amylotrophic lateral sclerosis,[9] but had no effect in normal subjects or in patients with renal failure undergoing chronic ambulatory peritoneal dialysis.[10][11] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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