Question

I am a breastfeeding mother and i want to know if it is safe to use Nespo? Is Nespo safe for nursing mother and child? Does Nespo extracts into breast milk? Does Nespo has any long term or short term side effects on infants? Can Nespo influence milk supply or can Nespo decrease milk supply in lactating mothers?

Answer by DrLact: About Nespo usage in lactation

The excretion of Nespo alfa in breastmilk or its effects on breastfed infants have not been studied. However, erythropoietin is a normal component of human milk and Nespo is immunologically and biologically indistinguishable from native erythropoietin. Intravenous Nespo has been given safely to newborn infants in doses much larger than those expected to appear in breastmilk. No special precautions are required during breastfeeding.

Nespo Side Effects in Breastfeeding

Enhancement of gastrointestinal tract maturation has been proposed as a function of erythropoietin in breastmilk.[1][8]

Nespo Possible Effects in Breastfeeding

In small studies, epoetin alfa administration decreased serum prolactin in patients with amylotrophic lateral sclerosis,[9] but had no effect in normal subjects or in patients with renal failure undergoing chronic ambulatory peritoneal dialysis.[10][11] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.