Question

I am a breastfeeding mother and i want to know if it is safe to use Ethyl 4-aminobenzoate? Is Ethyl 4-aminobenzoate safe for nursing mother and child? Does Ethyl 4-aminobenzoate extracts into breast milk? Does Ethyl 4-aminobenzoate has any long term or short term side effects on infants? Can Ethyl 4-aminobenzoate influence milk supply or can Ethyl 4-aminobenzoate decrease milk supply in lactating mothers?

Ethyl 4-aminobenzoate lactation summary

Ethyl 4-aminobenzoate is safe in breastfeeding
  • DrLact safety Score for Ethyl 4-aminobenzoate is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Ethyl 4-aminobenzoate is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Ethyl 4-aminobenzoate does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Ethyl 4-aminobenzoate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Ethyl 4-aminobenzoate usage in lactation

At latest update, relevant published data on excretion into breast milk were not found. Topical anesthetics (intended for dermatological or oral use) when properly used, show limited systemic absorption which is practically nil, with nil or non-significant systemic levels in the plasma and breast milk. Ethyl 4-aminobenzoate may induce appearance of methemoglobinemia and systemic toxicity if absorbed. Avoid use on the breast, otherwise, in case of use on the nipple, let it be done after a feed and wipe it out by thoroughly washing with water before the next feed. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance.

Answer by DrLact: About Ethyl 4-aminobenzoate usage in lactation

Topical Ethyl 4-aminobenzoate has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. Ethyl 4-aminobenzoate should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.