Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 7225? Is HSDB 7225 safe for nursing mother and child? Does HSDB 7225 extracts into breast milk? Does HSDB 7225 has any long term or short term side effects on infants? Can HSDB 7225 influence milk supply or can HSDB 7225 decrease milk supply in lactating mothers?

HSDB 7225 lactation summary

HSDB 7225 is safe in breastfeeding
  • DrLact safety Score for HSDB 7225 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 7225 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 7225 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 7225 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 7225 usage in lactation

At latest update, relevant published data on excretion into breast milk were not found. Topical anesthetics (intended for dermatological or oral use) when properly used, show limited systemic absorption which is practically nil, with nil or non-significant systemic levels in the plasma and breast milk. HSDB 7225 may induce appearance of methemoglobinemia and systemic toxicity if absorbed. Avoid use on the breast, otherwise, in case of use on the nipple, let it be done after a feed and wipe it out by thoroughly washing with water before the next feed. Do not apply creams, gels and other products that would contain paraffin (mineral oil) to avoid absorption by the infant since it is a hydrocarbon-derived substance.

Answer by DrLact: About HSDB 7225 usage in lactation

Topical HSDB 7225 has not been studied during breastfeeding, but is unlikely to affect her breastfed infant if it is applied away from the breast. HSDB 7225 should not be applied to the breast or nipple, because the infant may ingest the drug during nursing and it has been associated with severe methemoglobinemia.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.