Is (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine? Is (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine safe for nursing mother and child? Does (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine extracts into breast milk? Does (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine has any long term or short term side effects on infants? Can (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine influence milk supply or can (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine decrease milk supply in lactating mothers?

A minimal amount of clinical use of (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine during breastfeeding has been reported. Although no adverse reactions have been reported in the breastfed infants, an alternate drug may be preferred, especially while nursing a newborn or preterm infant. The manufacturer of the selegiling transdermal patch recommends that breastfeeding is not recommended during treatment and for 5 days after the final dose.

A woman took (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine 10 mg/day, levodopa 400 mg and benserazide 100 mg daily throughout pregnancy and continued them while breastfeeding her infant for 3 days. The child was followed for 10 years and no developmental abnormalities were found.[2] A woman with severe depression used a (R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine patch 6 mg per day during pregnancy and postpartum. She exclusively breastfed her infant for an unstated period of time. Pediatric follow-up at 5 months of age found that the infant was developing normally.[1]

(R)-(-)-N,alpha-Dimethyl-N-2-propinylphenethylamine can decrease serum prolactin in women with migraine,[3] and in those taking neuroleptic drugs.[4][5] The clinical relevance of these findings in nursing mothers is not known. The prolactin level in a mother with established lactation may not affect her ability to breastfeed.