Is 17beta-Estradiol 17-cyclopentylpropionate Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use 17beta-Estradiol 17-cyclopentylpropionate? Is 17beta-Estradiol 17-cyclopentylpropionate safe for nursing mother and child? Does 17beta-Estradiol 17-cyclopentylpropionate extracts into breast milk? Does 17beta-Estradiol 17-cyclopentylpropionate has any long term or short term side effects on infants? Can 17beta-Estradiol 17-cyclopentylpropionate influence milk supply or can 17beta-Estradiol 17-cyclopentylpropionate decrease milk supply in lactating mothers?

17beta-Estradiol 17-cyclopentylpropionate has not been studied during breastfeeding. However, the similar drug, estradiol valerate, has been used to suppress lactation, usually in combination with testosterone. Generally, 17beta-Estradiol 17-cyclopentylpropionate should be avoided in mothers wishing to breastfeed.

Another injection ester form of estradiol, estradiol valerate was previously used therapeutically to suppress lactation, usually in combination with testosterone.[3][4][5]A retrospective cohort study compared 371 women who received high-dose estrogen (either 3 mg of diethylstilbestrol or 150 mcg of ethinyl estradiol daily) during adolescence for adult height reduction to 409 women who did not receive estrogen. No difference in breastfeeding duration was found between the two groups, indicating that high-dose estrogen during adolescence has no effect on later breastfeeding.[6]