Is Clopentixol cis-(Z)- Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Clopentixol cis-(Z)-? Is Clopentixol cis-(Z)- safe for nursing mother and child? Does Clopentixol cis-(Z)- extracts into breast milk? Does Clopentixol cis-(Z)- has any long term or short term side effects on infants? Can Clopentixol cis-(Z)- influence milk supply or can Clopentixol cis-(Z)- decrease milk supply in lactating mothers?

Studies have failed to show any harmful effect on the infant. It is likely to be safer by using it orally on a daily basis than on IV slow-release dosage (depot).

Clopentixol cis-(Z)- is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited information indicates that maternal oral doses of up to 50 mg daily or depot injections of 72 mg every 2 weeks produce low levels in breastmilk and no detectable short-term adverse effects in the breastfed infants. No long-term data are available. Until more data are available, Clopentixol cis-(Z)- should be used with careful monitoring during breastfeeding. One international guideline recommends that women taking Clopentixol cis-(Z)- not breastfeed.[1]

Six women received Clopentixol cis-(Z)- during nursing. Five of the women were receiving 4 to 50 mg daily by mouth and one was receiving a depot injection of 72 mg every 2 weeks. Their breastfed infants range in age from 3 days to 10 months old, 5 of whom were 2 months or under. No immediate adverse effects such infant drowsiness were noted.[2]