Is UNII-21HMQ851IS Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-21HMQ851IS? Is UNII-21HMQ851IS safe for nursing mother and child? Does UNII-21HMQ851IS extracts into breast milk? Does UNII-21HMQ851IS has any long term or short term side effects on infants? Can UNII-21HMQ851IS influence milk supply or can UNII-21HMQ851IS decrease milk supply in lactating mothers?
UNII-21HMQ851IS lactation summary
- DrLact safety Score for UNII-21HMQ851IS is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-21HMQ851IS is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-21HMQ851IS does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-21HMQ851IS safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-21HMQ851IS usage in lactation
We are working on a comment for this product.
Answer by DrLact: About UNII-21HMQ851IS usage in lactation
UNII-21HMQ851IS is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited information indicates that maternal oral doses of up to 4 mg daily or depot injections of 40 mg every 2 weeks produce low levels in milk and breastfed infants' serum, and cause no adverse developmental consequences. Until more data are available, UNII-21HMQ851IS should be used with careful monitoring during breastfeeding.
UNII-21HMQ851IS Side Effects in Breastfeeding
A woman took UNII-21HMQ851IS 1 mg and nortriptyline 100 mg daily during pregnancy and UNII-21HMQ851IS 4 mg and nortriptyline 125 mg daily immediately postpartum. She exclusively breastfed her infant. Over a 4-month period, the infant showed no signs of adverse drug effects and had normal motor development with a maternal dosage of UNII-21HMQ851IS 2 mg daily and nortriptyline 75 mg daily.[2]
UNII-21HMQ851IS Possible Effects in Breastfeeding
UNII-21HMQ851IS can increase serum prolactin[3][4][5] and has caused galactorrrhea.[6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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