Question

I am a breastfeeding mother and i want to know if it is safe to use Caulophyllum thalictroides L. (Berberidaceae), extracts? Is Caulophyllum thalictroides L. (Berberidaceae), extracts safe for nursing mother and child? Does Caulophyllum thalictroides L. (Berberidaceae), extracts extracts into breast milk? Does Caulophyllum thalictroides L. (Berberidaceae), extracts has any long term or short term side effects on infants? Can Caulophyllum thalictroides L. (Berberidaceae), extracts influence milk supply or can Caulophyllum thalictroides L. (Berberidaceae), extracts decrease milk supply in lactating mothers?

Answer by DrLact: About Caulophyllum thalictroides L. (Berberidaceae), extracts usage in lactation

Caulophyllum thalictroides L. (Berberidaceae), extracts (Caulophyllum thalictroides) root contains N-methylcytosine, which has nicotine-like effects, and caulosaponin, a glycoside that constricts coronary vessels and may have oxytocic activity. It has been used to promote labor.[1][2][3] Caulophyllum thalictroides L. (Berberidaceae), extracts has no specific uses during breastfeeding. No data exist on the safety and efficacy of Caulophyllum thalictroides L. (Berberidaceae), extracts in nursing mothers or infants; however, it can cause severe gastrointestinal and cardiovascular toxicity, including in neonates whose mothers used it to stimulate labor. Most sources recommend strongly against its use during breastfeeding because of lack of safety data and potential toxicity.[2][4] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.

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