Is Ro 18-0647/002 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Ro 18-0647/002? Is Ro 18-0647/002 safe for nursing mother and child? Does Ro 18-0647/002 extracts into breast milk? Does Ro 18-0647/002 has any long term or short term side effects on infants? Can Ro 18-0647/002 influence milk supply or can Ro 18-0647/002 decrease milk supply in lactating mothers?

Anti-obesity product with a peripheral acting mechanism. Absorption of ingested fat is reduced by 35% due to local neutralization of lipase activity in the gut. Ro 18-0647/002 is not absorbed. At latest update, relevant information on excretion into breast milk was not found. However, because of pharmacokinetic data (a moderately high molecular-weight, a nil absorption, a high protein-binding-capacity), excretion of Ro 18-0647/002 into breast milk in significant levels is unlikely. Due to a lack of absorption, serum levels are likely nil. On long-standing basis, it may affect absorption of liposoluble vitamins (A, D, E, K) and beta-carotenes. This would be a reason to recommend a varied diet which should be rich in consumption of fruits, vegetables. Vitamin supplementation should also be considered. Nutritional status of the nursing mother should be monitored. Most of breastfeeding mothers recover the weight previous of pregnancy sooner than those who are not.

Because Ro 18-0647/002 is poorly absorbed orally, it is unlikely that any Ro 18-0647/002 is excreted into milk or absorbed by the infant. Therefore, it is unlikely to adversely affect the breastfed infant.