Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-95M8R751W8? Is UNII-95M8R751W8 safe for nursing mother and child? Does UNII-95M8R751W8 extracts into breast milk? Does UNII-95M8R751W8 has any long term or short term side effects on infants? Can UNII-95M8R751W8 influence milk supply or can UNII-95M8R751W8 decrease milk supply in lactating mothers?

UNII-95M8R751W8 lactation summary

UNII-95M8R751W8 usage has low risk in breastfeeding
  • DrLact safety Score for UNII-95M8R751W8 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-95M8R751W8 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-95M8R751W8 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-95M8R751W8 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-95M8R751W8 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-95M8R751W8 usage in lactation

Anti-obesity product with a peripheral acting mechanism. Absorption of ingested fat is reduced by 35% due to local neutralization of lipase activity in the gut. UNII-95M8R751W8 is not absorbed. At latest update, relevant information on excretion into breast milk was not found. However, because of pharmacokinetic data (a moderately high molecular-weight, a nil absorption, a high protein-binding-capacity), excretion of UNII-95M8R751W8 into breast milk in significant levels is unlikely. Due to a lack of absorption, serum levels are likely nil. On long-standing basis, it may affect absorption of liposoluble vitamins (A, D, E, K) and beta-carotenes. This would be a reason to recommend a varied diet which should be rich in consumption of fruits, vegetables. Vitamin supplementation should also be considered. Nutritional status of the nursing mother should be monitored. Most of breastfeeding mothers recover the weight previous of pregnancy sooner than those who are not.

Answer by DrLact: About UNII-95M8R751W8 usage in lactation

Because UNII-95M8R751W8 is poorly absorbed orally, it is unlikely that any UNII-95M8R751W8 is excreted into milk or absorbed by the infant. Therefore, it is unlikely to adversely affect the breastfed infant.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.