Is BMS 188667 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use BMS 188667? Is BMS 188667 safe for nursing mother and child? Does BMS 188667 extracts into breast milk? Does BMS 188667 has any long term or short term side effects on infants? Can BMS 188667 influence milk supply or can BMS 188667 decrease milk supply in lactating mothers?
BMS 188667 lactation summary
- DrLact safety Score for BMS 188667 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of BMS 188667 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that BMS 188667 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of BMS 188667 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using BMS 188667 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About BMS 188667 usage in lactation
Soluble fusion protein used for treatment of Rheumatoid Arthritis and other autoimmune diseases. Its high molecular weight and protein structure reduces its secretion into breast milk and make absorption by the gastrointestinal tract unlikely.
Answer by DrLact: About BMS 188667 usage in lactation
No information is available on the use of BMS 188667 during breastfeeding. BMS 188667 is a large genetically engineered fusion protein that interferes with T-cell activation. It has a molecular weight of 92,000. Only small amounts at most would be expected to enter breastmilk. If BMS 188667 is required by the mother, it is not a reason to discontinue breastfeeding.[1] However, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Alternate Drugs
Tocilizumab(Low Risk)
Anakinra(Low Risk)
Abatacept(Low Risk)
Rituximab(Low Risk)
Certolizumab Pegol(Safe)
Adalimumab(Safe)
Methotrexate(Low Risk)
Infliximab(Safe)
Sulfasalazine(Safe)
Hydroxychloroquine(Safe)
Chloroquine(Safe)
Penicillamine(Low Risk)
Etanercept(Safe)
Leflunomide(Dangerous)
Auranofin(Low Risk)