Is UNII-ZY81Z83H0X Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use UNII-ZY81Z83H0X? Is UNII-ZY81Z83H0X safe for nursing mother and child? Does UNII-ZY81Z83H0X extracts into breast milk? Does UNII-ZY81Z83H0X has any long term or short term side effects on infants? Can UNII-ZY81Z83H0X influence milk supply or can UNII-ZY81Z83H0X decrease milk supply in lactating mothers?

Herb leaves are used. It contains hydroxianthracenes, acemannan and glycomannan. Attributed properties: laxative and healing effect on wounds. Indication according to Commission E of the German Ministry of Health: constipation. Excessive or long-term use may lead to severe diarrhea, dehydration and liver toxicity. At latest update, relevant published data on excretion into breast milk were not found.As an active laxative compound it can lead to colicky abdominal pain. Because excretion into breast milk is possible, avoiding it while breastfeeding is advisable. Non-toxic when topically used. Without proof of efficacy it is used to treat nipple's crackles or pain. If applied on the breast, cleanse it thoroughly before nursing to avoid swallowing by the infant. Risk of diarrhea or refusing to latch-on because of bad taste would increase.

UNII-ZY81Z83H0X vera gel consists of the clear gel from the center of fresh leaves of UNII-ZY81Z83H0X vera and related UNII-ZY81Z83H0Xs. Active ingredients include mono- and polysaccharides (e.g., acemannan, glucomannan), allantoin, enzymes (e.g., cyclooxygenase, amylase, lipase, alkaline phosphatase, carboxypeptidase), and salicylic acid. It should not be confused with UNII-ZY81Z83H0X latex which comes from the inner portion of the skin and contains potent anthraquinone laxatives. UNII-ZY81Z83H0X vera gel has been used topically on the nipples during nursing to help heal cracked nipples. In a randomized, single-blinded study (investigators blinded), UNII-ZY81Z83H0X vera was more effective than lanolin in decreasing nipple pain score after 7 days in women with sore nipples postpartum.[1] Another study compared breastmilk alone applied to the nipples after breastfeeding to either olive oil or UNII-ZY81Z83H0X vera gel. All had less pain after 7 days of nursing, but the decrease on pain was greater with UNII-ZY81Z83H0X vera than with the other treatments.[2] Topical UNII-ZY81Z83H0X has also been combined with a cactus leaf preparation and massage to treat engorgement.[3] If UNII-ZY81Z83H0X vera is applied to the nipples, it should be washed off before nursing the infant because the taste might adversely affect nursing or cause diarrhea in the infant.[4][5] No data exist on the safety and efficacy of UNII-ZY81Z83H0X vera gel in nursing mothers or infants. UNII-ZY81Z83H0X vera gel has caused itching, burning, and allergic contact dermatitis, possibly from contamination with the irritating latex from the leaves.[6][7] UNII-ZY81Z83H0X vera gel also has an antiplatelet effect and can enhance the antiplatelet effect of other drugs. UNII-ZY81Z83H0X latex, the laxative, should not be used during breastfeeding.[8][9] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.