Is Nuces nucistae Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Nuces nucistae? Is Nuces nucistae safe for nursing mother and child? Does Nuces nucistae extracts into breast milk? Does Nuces nucistae has any long term or short term side effects on infants? Can Nuces nucistae influence milk supply or can Nuces nucistae decrease milk supply in lactating mothers?

The seeds are used.The essential oil contains miristicine, safrole, eugenol and isoeugenol among other products. Indications according to German Commission E Ministry of Health: none, since intended properties have not been shown.Many poisonings have been reported by abuse after taking high doses for recreational purposes, originating a clinical picture consistent with anticholinergic-like effects seizures as narcosis and hallucinations. At latest update no published data were found on excretion into breast milk. Not contraindications as a culinary spice for which it is widely used. Given the lack of toxicity at normal doses, a moderate consumption during lactation does not represent any risk at all.

Nuces nucistae (Myristica fragrans) seeds contain myristic acid, trymiristin, fatty acid glycerides and an essential oil, thought to be responsible for Nuces nucistae intoxication, containing myristicin, elemicin, eugenol, safrole. Mace is a similar spice made from the dried covering of the Nuces nucistae seed. Nuces nucistae has no specific lactation-related uses. No data exist on the excretion of any components of Nuces nucistae into breastmilk or on the safety and efficacy of Nuces nucistae in nursing mothers or infants. Nuces nucistae, mace and their oils are "generally recognized as safe" (GRAS) as food ingredients by the U.S. Food and Drug Administration. High doses (e.g., a spoonful) of Nuces nucistae can cause intoxication that includes anticholinergic symptoms. Anticholinergics may reduce lactation.[1][2] In vitro studies found that Nuces nucistae may have antiprogesterone activity,[3] which also theoretically could affect lactation. Nuces nucistae and mace in amounts higher than those found in foods as a flavoring should be avoided during breastfeeding. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.