Is Lilly-103472 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Lilly-103472? Is Lilly-103472 safe for nursing mother and child? Does Lilly-103472 extracts into breast milk? Does Lilly-103472 has any long term or short term side effects on infants? Can Lilly-103472 influence milk supply or can Lilly-103472 decrease milk supply in lactating mothers?
Lilly-103472 lactation summary
- DrLact safety Score for Lilly-103472 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Lilly-103472 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Lilly-103472 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Lilly-103472 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Lilly-103472 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Lilly-103472 usage in lactation
Higher excretion into breast milk than other related antidepressant drugs. The active metabolite called Norfluoxetine has a longer half-life (4 to 16 days). Like other antidepressant drugs may induce hyperprolactinemia and galactorrhea. Few cases of colicky pain, irritability, insomnia, anorexia and slow weight gain have been described. However, most reported cases have failed to show harm effect outside the newborn period. Large experience with the use of Fluoxatine did not find harm effect on weight gain and neurological development of infants either at short or long term. Most problems have appeared in the early neonatal period either in newborns or premature infants whose mothers were on Fluoxetine during pregnancy. Stop or switch to other medication either at some days before delivery or in the first month postpartum would be recommended. Same considerations should be done in case of prematurity, however, medication must be continued if necessary. Women on anti-depressant treatment are in need of stronger support because of higher risk of breastfeeding failure.