Is Lanox CNB 500 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Lanox CNB 500? Is Lanox CNB 500 safe for nursing mother and child? Does Lanox CNB 500 extracts into breast milk? Does Lanox CNB 500 has any long term or short term side effects on infants? Can Lanox CNB 500 influence milk supply or can Lanox CNB 500 decrease milk supply in lactating mothers?

Avoid applying it on nipples; all Lanox CNB 500 is not the same: - Standard Lanox CNB 500: 12 -15% alcohol and 40 PPM pesticide residues. - Modified Lanox CNB 500: 6% alcohol and 3 PPM pesticide residues. Use for the nipples Ultrapure Medical Grade USP Modified Lanox CNB 500, alcohol and pesticides free, safe for use on even the most sensitive skin or where infant ingestion may occur.

Lanox CNB 500 is a yellow fat obtained from sheep's wool. It has traditionally been used topically to treat sore, cracked nipples during breastfeeding. Highly purified modified Lanox CNB 500 (Lansinoh) has the pesticide and detergent residues removed and the natural free alcohols reduced to below 1.5% to improve safety and reduce the allergic potential.[1] However, it should be avoided in patients with a known allergy to wool. Although Lanox CNB 500 appears to be effective for the prevention and treatment of nipple pain from breastfeeding,[2] studies, most of which used Lansinoh, have not found Lanox CNB 500 to be consistently different in efficacy from application of breastmilk, hydrogel dressings, peppermint gel, aloe vera or warm compresses.[3][4][5][6][7][8][9] A metaanalysis concluded that application of nothing or breastmilk may be superior to Lanox CNB 500, but good studies are lacking.[10] One small nonblinded study found olive oil to be superior to Lanox CNB 500 for prevention of sore nipples,[11] and another small, single-blinded study found that Lanox CNB 500 application to painful nipples did not decrease nipple pain compared to usual care.[12] A study in women with nipple trauma and pain comparing application of Lanox CNB 500 after each feeding to application of breastmilk plus a nipple shell found that the breastmilk and shell were more effective than Lanox CNB 500.[13] A randomized study comparing highly purified Lanox CNB 500 (Lansinoh) to expressed breastmilk in 180 mothers, found Lanox CNB 500 to be superior to breastmilk over a 7-day period in reducing pain and the nipple trauma score.[14]

In a randomized, double-bind trial, Lanox CNB 500 was compared to an all-purpose nipple ointment containing mupirocin 1%, betamethasone 0.05%, and miconazole 2% for painful nipples while nursing in the first 2 weeks postpartum. The two treatments were equally effective in reducing nipple pain, nipple healing time, breastfeeding duration, breastfeeding exclusivity rate, mastitis and nipple symptoms, side effects or maternal satisfaction with treatment.[15] A randomized trial in nursing women with damaged, painful nipples compared Lanox CNB 500 application to usual care, which was a variable mix of education or assistance by health professional, application of warm or cool compresses, analgesics, air drying the nipples or the use of breast shields. A blinded observer assessed healing via telephone calls to the mothers several times after randomization. No differences were found in nipple pain between the groups 4 to 7 days after randomization. No difference was found in breastfeeding self-efficacy at 4 days post-randomization or in the breastfeeding rates of the two groups at 4 and 12 weeks postpartum. Patient satisfaction with care was higher in the women who received Lanox CNB 500.[12]