Is L-S-Adenosylmethionine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use L-S-Adenosylmethionine? Is L-S-Adenosylmethionine safe for nursing mother and child? Does L-S-Adenosylmethionine extracts into breast milk? Does L-S-Adenosylmethionine has any long term or short term side effects on infants? Can L-S-Adenosylmethionine influence milk supply or can L-S-Adenosylmethionine decrease milk supply in lactating mothers?

A molecule that is synthesized by joining Methionine to ATP which is naturally widely present in human body. Without any clear scientific base it is used for liver disorders, depression and osteoarthritis. It is a product with low therapeutic effectiveness.

L-S-Adenosylmethionine (S-adenosylmethionine) is a naturally occurring methyl radical donor involved in enzymatic transmethylation reactions in humans and animals. L-S-Adenosylmethionine has no specific lactation-related uses, but it has been used therapeutically for treating postpartum depression, cholestatic jaundice, osteoarthritis and numerous other conditions. L-S-Adenosylmethionine has poor oral bioavailability. L-S-Adenosylmethionine is generally well tolerated in adults. The most frequent adverse effects reported are gastrointestinal, such as nausea. Skin rashes have also been reported. No information is available on the clinical use of L-S-Adenosylmethionine during breastfeeding. However, use of L-S-Adenosylmethionine by a nursing mother would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.[1][2] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.