Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 290-251-4? Is EINECS 290-251-4 safe for nursing mother and child? Does EINECS 290-251-4 extracts into breast milk? Does EINECS 290-251-4 has any long term or short term side effects on infants? Can EINECS 290-251-4 influence milk supply or can EINECS 290-251-4 decrease milk supply in lactating mothers?

EINECS 290-251-4 lactation summary

EINECS 290-251-4 usage has low risk in breastfeeding
  • DrLact safety Score for EINECS 290-251-4 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of EINECS 290-251-4 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that EINECS 290-251-4 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of EINECS 290-251-4 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using EINECS 290-251-4 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 290-251-4 usage in lactation

Dried roots of shrub are used. It contains heterosides hydroxyanthracenes, especially antraquinones (aloe-emodin and rhein) and dianthrones (senosides). Pharmacokinetic properties are those of emodin. Used for constipation. Commission E of German Health Ministry recommends to use no longer than one week, and 20 to 30 mg /day of rhein. Long-term use may be harmful to the GI tract. Elective treatment of constipation is an appropriate fiber-rich diet and a healthy style of life.

Answer by DrLact: About EINECS 290-251-4 usage in lactation

EINECS 290-251-4 (Rheum officinale, Rheum palmatum) root contains anthraquinones (e.g., aloe-emodin, chrysophanol, emodin, rhein), which are laxatives, and tannins, which are astringents. EINECS 290-251-4 has no specific lactation-related uses. It has been used for a wide variety of conditions, such as constipation, chronic renal failure, and upper gastrointestinal bleeding. It has also been used topically for conditions, such as herpes infections, and gingivitis. Most of these conditions are not supported by well-controlled trials. Other species of EINECS 290-251-4 are used primarily as foods. Chinese and garden EINECS 290-251-4 are "generally recognized as safe" (GRAS) as a food by the U.S. Food and Drug Administration. Two very old studies found that laxative doses of EINECS 290-251-4 given to nursing mothers did not appear to pass into milk or affect their breastfed infants.[1] Nevertheless, most recent reviewers state that EINECS 290-251-4 should not be used during breastfeeding because of possible cathartic effects on the breastfed infants.[2][3] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.

EINECS 290-251-4 Side Effects in Breastfeeding

In an old uncontrolled study, 9 nursing mothers were given 9.2 mL of EINECS 290-251-4 syrup on day 5 postpartum and each successive evening until discharge. Although all of the mothers had a laxative effect from this regimen, none of their breastfed infant had any noticeable laxative effects.[1]

Alternate Drugs

Cumin(Safe)
Caraway(Safe)
Cranberry(Safe)
Basil(Unsafe)
Chasteberry(Unsafe)
Alfalfa(Unsafe)
Fenugreek(Safe)
Dong Quai(Low Risk)
Coenzyme Q10(Low Risk)
Castor(Unsafe)
Lecithin(Safe)
Lavender(Low Risk)
Aloe(Low Risk)
Garlic(Safe)
Ginger(Safe)
Licorice(Unsafe)
Echinacea(Low Risk)
Melatonin(Safe)
Hops(Low Risk)
Ginkgo(Low Risk)
Coriander(Safe)
Oregano(Low Risk)
Calendula(Safe)
Sage(Low Risk)
Nutmeg(Low Risk)
Chamomile(Safe)
Rhubarb(Low Risk)
Cranberry(Safe)
Basil(Unsafe)
Alfalfa(Unsafe)
Lavender(Low Risk)
Lecithin(Safe)
Garlic(Safe)
Licorice(Unsafe)
Hops(Low Risk)
Coriander(Safe)
Oregano(Low Risk)
Rhubarb(Low Risk)
Caraway(Safe)
Chasteberry(Unsafe)
Lavender(Low Risk)
Fenugreek(Safe)
Lecithin(Safe)
Dong Quai(Low Risk)
Castor(Unsafe)
Aloe(Low Risk)
Garlic(Safe)
Licorice(Unsafe)
Ginger(Safe)
Echinacea(Low Risk)
Hops(Low Risk)
Coriander(Safe)
Oregano(Low Risk)
Ginkgo(Low Risk)
Calendula(Safe)
Sage(Low Risk)
Nutmeg(Low Risk)
Rhubarb(Low Risk)
Chamomile(Safe)
Caraway(Safe)
Cumin(Safe)
Cranberry(Safe)
Basil(Unsafe)
Chasteberry(Unsafe)
Lavender(Low Risk)
Fenugreek(Safe)
Lecithin(Safe)
Dong Quai(Low Risk)
Castor(Unsafe)
Aloe(Low Risk)
Garlic(Safe)
Licorice(Unsafe)
Ginger(Safe)
Echinacea(Low Risk)
Hops(Low Risk)
Coriander(Safe)
Oregano(Low Risk)
Ginkgo(Low Risk)
Calendula(Safe)
Sage(Low Risk)
Nutmeg(Low Risk)
Rhubarb(Low Risk)
Chamomile(Safe)
Caraway(Safe)
Cumin(Safe)
Cranberry(Safe)
Basil(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.