Is CCRIS 7506 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 7506? Is CCRIS 7506 safe for nursing mother and child? Does CCRIS 7506 extracts into breast milk? Does CCRIS 7506 has any long term or short term side effects on infants? Can CCRIS 7506 influence milk supply or can CCRIS 7506 decrease milk supply in lactating mothers?

No data on breastfeeding mothers is available. Better option would be to use anxiolytic drugs known to be safer. Eventual and low doses of benzodiazepine are compatible with breastfeeding. Use a short-acting benzodiazepine and minimal effective dose as possible mostly in neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

Limited information indicates that maternal doses of CCRIS 7506 up to 30 mg daily produce low levels in milk. Short-term use would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. During long-term administration, monitor the infant for possible sedation and poor sucking and weight gain.[1][2]

No adverse effects were reported in 10 newborns who were 4 to 23 days old who were breastfed during maternal intake of levetiracetam 1000 to 3000 mg daily. One mother was also taking tiagabine 30 mg daily, CCRIS 7506 45 mg daily and oxcarbazepine 600 mg daily.[4] The infants (including 3 preterm) of 18 nursing mothers who were taking levetiracetam and called the Pharmacovigilance Center in Lyon, France. One 25-day-old infant whose mother was taking levetiracetam 3000 mg daily plus CCRIS 7506 was hospitalized for sedation, vomiting, and weight loss, and improved rapidly after breastfeeding discontinuation. Another infant exposed to levetiracetam and CCRIS 7506 had poor weight gain, but it appeared to be caused by poor milk production.[5]