Question

I am a breastfeeding mother and i want to know if it is safe to use Dicycloverine Hydrochloride? Is Dicycloverine Hydrochloride safe for nursing mother and child? Does Dicycloverine Hydrochloride extracts into breast milk? Does Dicycloverine Hydrochloride has any long term or short term side effects on infants? Can Dicycloverine Hydrochloride influence milk supply or can Dicycloverine Hydrochloride decrease milk supply in lactating mothers?

Dicycloverine Hydrochloride lactation summary

Dicycloverine Hydrochloride is unsafe in breastfeeding
  • DrLact safety Score for Dicycloverine Hydrochloride is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Dicycloverine Hydrochloride may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Dicycloverine Hydrochloride may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Dicycloverine Hydrochloride .
  • It is recommended to evaluate the advantage of not breastfeeding while using Dicycloverine Hydrochloride Vs not using Dicycloverine Hydrochloride And continue breastfeeding.
  • While using Dicycloverine Hydrochloride Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Dicycloverine Hydrochloride usage in lactation

Because of high protein-binding capacity, clinically significant excretion into breast milk is unlikely. However, both the mother and the infant would benefit of the use of a better-known alternative drug that would be safer while breastfeeding, especially in the neonatal period and in case of prematurity. In spite of a low excretion into breast milk, it has been described a case of severe apnea in a 12 days old infant. A causal connection between those features and this drug has not been clearly defined (Briggs 2011, p. 410). It is licensed for use in children from 6 months of age as intestinal antispasmodic and treatment of Familial Mediterranean Fever, so there would be less risky when used by the breastfeeding mother.
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