Is Goldenseal powder Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Goldenseal powder? Is Goldenseal powder safe for nursing mother and child? Does Goldenseal powder extracts into breast milk? Does Goldenseal powder has any long term or short term side effects on infants? Can Goldenseal powder influence milk supply or can Goldenseal powder decrease milk supply in lactating mothers?

Goldenseal powder (Hydrastis canadensis) root contains berberine and other isoquinoline alkaloids. Goldenseal powder has traditionally been used as an anti-infective both systemically and topically, although high-quality studies of its efficacy and safety are lacking. It has also been used to mask illicit drugs in the urine, although it appears to be ineffective with modern laboratory methods. Goldenseal powder has been used topically by nursing mothers to treat sore nipples.[1] No data exist on the excretion of any components of Goldenseal powder into breastmilk or on the safety and efficacy of Goldenseal powder in nursing mothers. Berberine can displace bilirubin from serum albumin, causing concern about exposure of newborn infants, because bilirubin can build up in the infant's brain, causing brain damage. However, the extent of berberine's passage from the mother to the infant is unknown. Most sources recommend avoiding exposure of neonates to Goldenseal powder via breastfeeding or otherwise.[2][3][4] Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.