Is Hexamethylpararosaniline chloride Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Hexamethylpararosaniline chloride? Is Hexamethylpararosaniline chloride safe for nursing mother and child? Does Hexamethylpararosaniline chloride extracts into breast milk? Does Hexamethylpararosaniline chloride has any long term or short term side effects on infants? Can Hexamethylpararosaniline chloride influence milk supply or can Hexamethylpararosaniline chloride decrease milk supply in lactating mothers?
Hexamethylpararosaniline chloride lactation summary
- DrLact safety Score for Hexamethylpararosaniline chloride is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Hexamethylpararosaniline chloride is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Hexamethylpararosaniline chloride does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Hexamethylpararosaniline chloride safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Hexamethylpararosaniline chloride usage in lactation
We are working on a comment for this product.
Answer by DrLact: About Hexamethylpararosaniline chloride usage in lactation
Hexamethylpararosaniline chloride (crystal violet) was used in the past to treat oral and nipple thrush during breastfeeding. Hexamethylpararosaniline chloride is potentially toxic to the mucous membranes, causing ulceration,[1][2][3][4] and potentially tattooing the skin. It can also interact with DNA[5], is carcinogenic and mutagenic in rodents, and occasionally causes allergic sensitization, with cross reactions to other triphenylmethane dyes.[6] Its use has been severely curtailed by authorities in England and Australia.[7][8] It is also very messy, staining skin and clothing. A 2001 survey of the members of the Academy of Breastfeeding Medicine (ABM) found that Hexamethylpararosaniline chloride is rarely (1 to 2% of respondents) used by breastfeeding experts for initial treatment of oral thrush and is very infrequently (3 to 4% of respondents) used for recurrent or persistent thrush.[9] ABM guidelines for treating Candida infection of the nipples state that an aqueous solution of Hexamethylpararosaniline chloride of less than 0.5% can be used for no more than 7 days on the nipple.[10] However, safer alternatives for treating thrush are available.[11]
Hexamethylpararosaniline chloride Side Effects in Breastfeeding
Hexamethylpararosaniline chloride has caused oral ulceration in breastfed infants treated with 1% or 2% solution applied to the mouth and tongue for thrush.[1][2][3] A 2-week-old exclusively breastfed infant was treated for oral thrush with aqueous 1% Hexamethylpararosaniline chloride solution twice daily for 1 day. The parents discontinued it because they thought it was causing airway discomfort. After 2 days, it was restarted at 4 times a day. Cough and difficulty feeding developed after 1 day and the infant was then admitted to the hospital, ultimately requiring intubation.[4]