Question

I am a breastfeeding mother and i want to know if it is safe to use Methyl Violet 5BNO? Is Methyl Violet 5BNO safe for nursing mother and child? Does Methyl Violet 5BNO extracts into breast milk? Does Methyl Violet 5BNO has any long term or short term side effects on infants? Can Methyl Violet 5BNO influence milk supply or can Methyl Violet 5BNO decrease milk supply in lactating mothers?

Methyl Violet 5BNO lactation summary

Methyl Violet 5BNO is safe in breastfeeding
  • DrLact safety Score for Methyl Violet 5BNO is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Methyl Violet 5BNO is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Methyl Violet 5BNO does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Methyl Violet 5BNO safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Methyl Violet 5BNO usage in lactation

We are working on a comment for this product.

Answer by DrLact: About Methyl Violet 5BNO usage in lactation

Methyl Violet 5BNO (crystal violet) was used in the past to treat oral and nipple thrush during breastfeeding. Methyl Violet 5BNO is potentially toxic to the mucous membranes, causing ulceration,[1][2][3][4] and potentially tattooing the skin. It can also interact with DNA[5], is carcinogenic and mutagenic in rodents, and occasionally causes allergic sensitization, with cross reactions to other triphenylmethane dyes.[6] Its use has been severely curtailed by authorities in England and Australia.[7][8] It is also very messy, staining skin and clothing. A 2001 survey of the members of the Academy of Breastfeeding Medicine (ABM) found that Methyl Violet 5BNO is rarely (1 to 2% of respondents) used by breastfeeding experts for initial treatment of oral thrush and is very infrequently (3 to 4% of respondents) used for recurrent or persistent thrush.[9] ABM guidelines for treating Candida infection of the nipples state that an aqueous solution of Methyl Violet 5BNO of less than 0.5% can be used for no more than 7 days on the nipple.[10] However, safer alternatives for treating thrush are available.[11]

Methyl Violet 5BNO Side Effects in Breastfeeding

Methyl Violet 5BNO has caused oral ulceration in breastfed infants treated with 1% or 2% solution applied to the mouth and tongue for thrush.[1][2][3] A 2-week-old exclusively breastfed infant was treated for oral thrush with aqueous 1% Methyl Violet 5BNO solution twice daily for 1 day. The parents discontinued it because they thought it was causing airway discomfort. After 2 days, it was restarted at 4 times a day. Cough and difficulty feeding developed after 1 day and the infant was then admitted to the hospital, ultimately requiring intubation.[4]

Synonyms of Methyl Violet 5BNO

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.