Question

I am a breastfeeding mother and i want to know if it is safe to use Methylrosanilinii chloridum [INN-Latin]? Is Methylrosanilinii chloridum [INN-Latin] safe for nursing mother and child? Does Methylrosanilinii chloridum [INN-Latin] extracts into breast milk? Does Methylrosanilinii chloridum [INN-Latin] has any long term or short term side effects on infants? Can Methylrosanilinii chloridum [INN-Latin] influence milk supply or can Methylrosanilinii chloridum [INN-Latin] decrease milk supply in lactating mothers?

Methylrosanilinii chloridum [INN-Latin] lactation summary

Methylrosanilinii chloridum [INN-Latin] is safe in breastfeeding
  • DrLact safety Score for Methylrosanilinii chloridum [INN-Latin] is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Methylrosanilinii chloridum [INN-Latin] is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Methylrosanilinii chloridum [INN-Latin] does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Methylrosanilinii chloridum [INN-Latin] safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Methylrosanilinii chloridum [INN-Latin] usage in lactation

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Answer by DrLact: About Methylrosanilinii chloridum [INN-Latin] usage in lactation

Methylrosanilinii chloridum [INN-Latin] (crystal violet) was used in the past to treat oral and nipple thrush during breastfeeding. Methylrosanilinii chloridum [INN-Latin] is potentially toxic to the mucous membranes, causing ulceration,[1][2][3][4] and potentially tattooing the skin. It can also interact with DNA[5], is carcinogenic and mutagenic in rodents, and occasionally causes allergic sensitization, with cross reactions to other triphenylmethane dyes.[6] Its use has been severely curtailed by authorities in England and Australia.[7][8] It is also very messy, staining skin and clothing. A 2001 survey of the members of the Academy of Breastfeeding Medicine (ABM) found that Methylrosanilinii chloridum [INN-Latin] is rarely (1 to 2% of respondents) used by breastfeeding experts for initial treatment of oral thrush and is very infrequently (3 to 4% of respondents) used for recurrent or persistent thrush.[9] ABM guidelines for treating Candida infection of the nipples state that an aqueous solution of Methylrosanilinii chloridum [INN-Latin] of less than 0.5% can be used for no more than 7 days on the nipple.[10] However, safer alternatives for treating thrush are available.[11]

Methylrosanilinii chloridum [INN-Latin] Side Effects in Breastfeeding

Methylrosanilinii chloridum [INN-Latin] has caused oral ulceration in breastfed infants treated with 1% or 2% solution applied to the mouth and tongue for thrush.[1][2][3] A 2-week-old exclusively breastfed infant was treated for oral thrush with aqueous 1% Methylrosanilinii chloridum [INN-Latin] solution twice daily for 1 day. The parents discontinued it because they thought it was causing airway discomfort. After 2 days, it was restarted at 4 times a day. Cough and difficulty feeding developed after 1 day and the infant was then admitted to the hospital, ultimately requiring intubation.[4]

Synonyms of Methylrosanilinii chloridum [INN-Latin]

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