Is NSC 3090 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NSC 3090? Is NSC 3090 safe for nursing mother and child? Does NSC 3090 extracts into breast milk? Does NSC 3090 has any long term or short term side effects on infants? Can NSC 3090 influence milk supply or can NSC 3090 decrease milk supply in lactating mothers?
NSC 3090 lactation summary
- DrLact safety Score for NSC 3090 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of NSC 3090 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that NSC 3090 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of NSC 3090 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NSC 3090 usage in lactation
We are working on a comment for this product.
Answer by DrLact: About NSC 3090 usage in lactation
NSC 3090 (crystal violet) was used in the past to treat oral and nipple thrush during breastfeeding. NSC 3090 is potentially toxic to the mucous membranes, causing ulceration,[1][2][3][4] and potentially tattooing the skin. It can also interact with DNA[5], is carcinogenic and mutagenic in rodents, and occasionally causes allergic sensitization, with cross reactions to other triphenylmethane dyes.[6] Its use has been severely curtailed by authorities in England and Australia.[7][8] It is also very messy, staining skin and clothing. A 2001 survey of the members of the Academy of Breastfeeding Medicine (ABM) found that NSC 3090 is rarely (1 to 2% of respondents) used by breastfeeding experts for initial treatment of oral thrush and is very infrequently (3 to 4% of respondents) used for recurrent or persistent thrush.[9] ABM guidelines for treating Candida infection of the nipples state that an aqueous solution of NSC 3090 of less than 0.5% can be used for no more than 7 days on the nipple.[10] However, safer alternatives for treating thrush are available.[11]
NSC 3090 Side Effects in Breastfeeding
NSC 3090 has caused oral ulceration in breastfed infants treated with 1% or 2% solution applied to the mouth and tongue for thrush.[1][2][3] A 2-week-old exclusively breastfed infant was treated for oral thrush with aqueous 1% NSC 3090 solution twice daily for 1 day. The parents discontinued it because they thought it was causing airway discomfort. After 2 days, it was restarted at 4 times a day. Cough and difficulty feeding developed after 1 day and the infant was then admitted to the hospital, ultimately requiring intubation.[4]