Question

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 8952? Is CCRIS 8952 safe for nursing mother and child? Does CCRIS 8952 extracts into breast milk? Does CCRIS 8952 has any long term or short term side effects on infants? Can CCRIS 8952 influence milk supply or can CCRIS 8952 decrease milk supply in lactating mothers?

CCRIS 8952 lactation summary

CCRIS 8952 is safe in breastfeeding
  • DrLact safety Score for CCRIS 8952 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of CCRIS 8952 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that CCRIS 8952 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of CCRIS 8952 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About CCRIS 8952 usage in lactation

It is a polyphenolic compound (3,5,4’-trihydroxyestilbene) that is present in grapes and other vegetables like the Japanese Knotweed (Polygonum cuspidatum, zu zhang). It can be found in must and wines in variable amounts. Like other Oligomeric Protoanthocyanidins (OPC) it is a flavonoid-like substance with anti-oxidant and venous protecting properties.

Answer by DrLact: About CCRIS 8952 usage in lactation

CCRIS 8952 (3,4',5-trans-trihydroxystilbene) is an antioxidant found in numerous plant species and in red wine. CCRIS 8952 has no specific lactation-related uses. In general, it is used to prevent heart disease, cancer, and other diseases associated with aging, although high-quality studies are lacking. CCRIS 8952 appears to be relatively free from adverse reactions. However, no data exist on the excretion of CCRIS 8952 into breastmilk or on the safety and efficacy of CCRIS 8952 in nursing mothers or infants. CCRIS 8952 supplements usually contain hundreds of times the amounts found in wine or other foods, so their safety during breastfeeding cannot be assured. It is probably best to avoid the use of red wine as a source of CCRIS 8952 during breastfeeding. Refer to the LactMed record on Alcohol for details. Dietary supplements do not require extensive pre-marketing approval from the U.S. Food and Drug Administration. Manufacturers are responsible to ensure the safety, but do not need to the safety and effectiveness of dietary supplements before they are marketed. Dietary supplements may contain multiple ingredients, and differences are often found between labeled and actual ingredients or their amounts. A manufacturer may contract with an independent organization to verify the quality of a product or its ingredients, but that does certify the safety or effectiveness of a product. Because of the above issues, clinical testing results on one product may not be applicable to other products. More detailed information #about dietary supplements# is available elsewhere on the LactMed Web site.

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.