Is OPC-1085 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use OPC-1085? Is OPC-1085 safe for nursing mother and child? Does OPC-1085 extracts into breast milk? Does OPC-1085 has any long term or short term side effects on infants? Can OPC-1085 influence milk supply or can OPC-1085 decrease milk supply in lactating mothers?

• DrLact safety Score for OPC-1085 is 5 out of 8 which is considered Unsafe as per our analyses.
• A safety Score of 5 indicates that usage of OPC-1085 may cause serious side effects in breastfed baby.
• Our study of different scientific research indicates that OPC-1085 may cause moderate to high side effects or may affect milk supply in lactating mother.
• Our suggestion is to use safer alternate options rather than using OPC-1085 .
• It is recommended to evaluate the advantage of not breastfeeding while using OPC-1085 Vs not using OPC-1085 And continue breastfeeding.
• While using OPC-1085 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
• Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

At date of last update were not found published data on its excretion into breast milk, Pharmacokinetic data (low protein-binding capacity) make likely excretion into breast milk in amounts that could be significant. Until more information on this drug is available, it is preferred other options that are known to be safer, especially during the neonatal period or in cases of prematurity. Because of a small dose and low absorption to the plasma in a majority of ophthalmic preparations that are topically used, a significant excretion into the milk is unlikely, thus it is considered of very low risk while breastfeeding in this cases. It would be advisable to press on the lacrimal area or tightly close the eyes for a couple of minutes (nasolacrimal occlusion) to minimize the systemic absorption.