Is UNII-5QS67N4551 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use UNII-5QS67N4551? Is UNII-5QS67N4551 safe for nursing mother and child? Does UNII-5QS67N4551 extracts into breast milk? Does UNII-5QS67N4551 has any long term or short term side effects on infants? Can UNII-5QS67N4551 influence milk supply or can UNII-5QS67N4551 decrease milk supply in lactating mothers?

UNII-5QS67N4551 [human] is a serine proteinase inhibitor derived from human plasma that is used in treating hereditary angioedema. Breastmilk levels of UNII-5QS67N4551 have not been measured after exogenous administration in humans. Because of its large molecular weight, amounts in milk are expected to be small. Any UNII-5QS67N4551 in breastmilk is probably destroyed in the infant's gastrointestinal tract and not absorbed, except perhaps in neonates. Various international consensus panels state that human plasma-derived UNII-5QS67N4551 is considered to be the therapy of choice for both treatment and prophylaxis of maternal hereditary angioedema during lactation.[1][2]

Three patients with hereditary angioedema received UNII-5QS67N4551 concentrate on 12 occasions to relieve abdominal edematous episodes during breastfeeding. No adverse reactions were reported.[3] In a case series spanning 12 years, 21 mothers with hereditary angioedema breastfed their infants for a median duration of 4.8 months (range 1 to 34 months) while receiving UNII-5QS67N4551 concentrate as needed. No side effects occurred tin the breastfed infants.[4] A pregnant woman with severe hereditary angioedema required 500 IU of C1 inhibitor concentrate every 2 days to maintain her pregnancy. Postpartum, she received 500 IU on demand while breastfeeding. She used 88 vitals during her 6-month breastfeeding (extent not stated) period. No side effects or viral transmission were reported and or virus anti-C1-INH antibodies were not detected.[5] A woman with hereditary angioedema received C1 inhibitor concentrate 1000 units every week during pregnancy. Postpartum she used 500 units as needed. She and her breastfed infant were reportedly healthy.[6]