Question

I am a breastfeeding mother and i want to know if it is safe to use Glycyrrhetinic Acid? Is Glycyrrhetinic Acid safe for nursing mother and child? Does Glycyrrhetinic Acid extracts into breast milk? Does Glycyrrhetinic Acid has any long term or short term side effects on infants? Can Glycyrrhetinic Acid influence milk supply or can Glycyrrhetinic Acid decrease milk supply in lactating mothers?

Glycyrrhetinic Acid lactation summary

Glycyrrhetinic Acid usage has low risk in breastfeeding
  • DrLact safety Score for Glycyrrhetinic Acid is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Glycyrrhetinic Acid may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Glycyrrhetinic Acid may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Glycyrrhetinic Acid low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Glycyrrhetinic Acid We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Glycyrrhetinic Acid usage in lactation

Glycyrrhizinic acid derivative that is extracted from the root of licorice.Anti-inflammatory effect when topically applied (skin, mouth, throat and rectum). At latest update no published data on excretion into breast milk were found. It locally enhances the activity of hydrocortisone by inactivating a cortisol inhibiting enzyme, which can cause toxicity after systemic administration (see info on Licorice).It is unknown the level of absorption after dermal and oral rinses or application, with a reported case of systemic toxicity following topical use. Hence, it is not recommended a prolonged use of this product during lactation.It can cause contact dermatitis. Avoid applying it on the breast, otherwise, clean it thoroughly before breastfeeding.

Alternate Drugs for Treatment of wounds and ulcers: Cicatrizants & Enzymes. Act D03

Nitroglycerin(Safe)
Becaplermin(Low Risk)
Enoxolone(Low Risk)
Hydrocolloid Patch(Safe)
Isosorbide Dinitrate(Low Risk)
Glyceryl Trinitrate(Safe)
Pantothenic Acid(Safe)
Collagenase(Safe)
Panthenol(Safe)
Trinitrin(Safe)
Trinitroglycerin(Safe)
Glycyrrhetic Acid(Low Risk)
Vitamin B3(Safe)
Vitamin B5(Safe)
Clostridiopeptidase A(Safe)
Rhpdgf-Bb(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.